| Autor: |
Yuxuan Liu, Zhimin Gu, Hui Cao, Pranita Kaphle, Junhua Lyu, Yuannyu Zhang, Wenhuo Hu, Stephen S. Chung, Kathryn E. Dickerson, Jian Xu |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-26582-4 |
| Popis: |
Identifying how genetic alterations cooperate in cancer is challenging. Here the authors analyze leukemia mouse models with both oncogenic NRAS and EZH2 mutations using single-cell RNA-sequencing, evaluate oncogenic cooperation, and identify GEM as a regulator of leukemia-initiating cells. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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