| Autor: |
Qing Ye, Jing Li, Xiaoyan Wang, Xianzeng Zhang, Jun Lin, Yuting Huo, Zhengzhen Sun, Shusen Xie, Zheng Huang |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Brazilian Journal of Otorhinolaryngology, Vol 86, Iss 5, Pp 617-625 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1808-8694 |
| DOI: |
10.1016/j.bjorl.2019.04.002 |
| Popis: |
Introduction: Nasopharyngeal carcinoma, an epithelial-derived malignant tumor which because of its anatomical location and atypical early symptoms, when diagnosed invasion and metastasis often have occurred. This requires a better understanding of the development mechanism, identifying diagnostic markers, and developing new treatment strategies. Objective: To study the relationship of LMP1 and Cripto-1 in nasopharyngeal carcinoma. Methods: The expression of LMP1 and Cripto-1 in specimens obtained from nasopharyngeal carcinoma patients (n = 42) and nasopharyngitis patients (n = 22) were examined. The expression of LMP1 and Cripto-1 in LMP1-negative and LMP1-positive (CNE1-LMP1) cells were also examined. Results: The expression of LMP1 and Cripto-1 was significantly higher in nasopharyngeal carcinoma than in nasopharyngitis (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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