Immunological changes in a cohort of COVID-19 survivors: Mansoura University experience [version 2; peer review: 2 approved]

Autor: Eman Khashaba, Ahmed El-Mesery, Marwa O. Elmaria, Nermin Abo El Kheir, Elsayed A. Eid, Asem Hewidy, Rehab Ahmad Elmorsey, Heba Wagih Abdelwahab, Doaa Shahin, Tamer Elhadidy
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: F1000Research, Vol 12 (2023)
Druh dokumentu: article
ISSN: 2046-1402
DOI: 10.12688/f1000research.134565.2
Popis: Background: COVID-19 is a global pandemic that has affected millions of people all over the world since 2019. Infection with COVID-19 initiates a humoral immune response that produces antibodies against specific viral antigens, which in turn is supposed to provide immunity against reinfection for a period of time. The aim of this research was to study the kinetics of IgM and IgG antibodies against SARS-CoV-2. Methods: One hundred and seventeen post-COVID-19 participants were enrolled in the study. Qualitative assessment of IgM and IgG antibodies over six months (three visits) post recovery was conducted. Results: The current study revealed a significant reduction in IgM and IgG titers between the first and second visits (p
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