Diabetic family history in young Japanese persons with normal glucose tolerance associates with k-means clustering of glucose response to oral glucose load, insulinogenic index and Matsuda index

Autor:	Norimitsu Murai, Naoko Saito, Sayuri Nii, Yuto Nishikawa, Asami Suzuki, Eriko Kodama, Tatsuya Iida, Kentaro Mikura, Hideyuki Imai, Mai Hashizume, Yasuyoshi Kigawa, Rie Tadokoro, Chiho Sugisawa, Kei Endo, Toru Iizaka, Fumiko Otsuka, Shun Ishibashi, Shoichiro Nagasaka
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Oral glucose tolerance test Normal glucose tolerance Insulinogenic index Matsuda index K-means clustering Physiology QP1-981 Biochemistry QD415-436
Zdroj:	Metabolism Open, Vol 15, Iss , Pp 100196- (2022)
Druh dokumentu:	article
ISSN:	2589-9368
DOI:	10.1016/j.metop.2022.100196
Popis:	Aims: The present study aimed to clarify the relationships between diabetic family history (FH), and dysglycemic response to the oral glucose tolerance test (OGTT), insulin secretion, and insulin sensitivity in young Japanese persons with normal glucose tolerance (NGT). Methods: We measured plasma glucose (PG) and immunoreactive insulin levels in 1,309 young Japanese persons (age
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a337aed0c1fb40b79fb4461dd5a0ac4f Zobrazit plný text záznamu View record in DOAJ