| Autor: |
K. H. Park, S. J. Kim, M. J. Hwang, H. J. Song, Y. J. Park |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
eXPRESS Polymer Letters, Vol 11, Iss 1, Pp 14-20 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1788-618X |
| DOI: |
10.3144/expresspolymlett.2017.3 |
| Popis: |
In this study, nucleation and growth of bone-like hydroxyapatite (HAp) mineral in modified simulated body fluids (m-SBF) were induced on chitosan (CS) substrates, which were prepared by spin coating of chitosan on Ti substrate. The m-SBF showed a two fold increase in the concentrations of calcium and phosphate ions compared to SBF, and the post-NaOH treatment provided stabilization of the coatings. The calcium phosphate/chitosan composite prepared in m-SBF showed homogeneous distribution of approximately 350 nm-sized spherical clusters composed of octacalcium phosphate (OCP; Ca8H2(PO4)6·5H2O) crystalline structure. Chitosan provided a control over the size of calcium phosphate prepared by immersion in m-SBF, and post-NaOH treatment supported the binding of calcium phosphate compound on the Ti surface. Post-NaOH treatment increased hydrophilicity and crystallinity of carbonate apatite, which increased its potential for biomedical application. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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