| Autor: |
Tzu-Yin Chen, Miki M.C. Wang, Sheng-Kuo Hsieh, Meng-Huang Hsieh, Wen-Ying Chen, Jason T.C. Tzen |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Journal of Functional Foods, Vol 48, Iss , Pp 1-8 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2018.06.020 |
| Popis: |
Strictinin isolated from Pu’er tea was demonstrated to inhibit pancreatic lipase in vitro. In an olive oil tolerance test, the administration of strictinin (100 mg/kg) significantly reduced the blood triglyceride level and increased the fecal oil content of C57BL6 mice. In a long-term animal study, the body weight gained via high-fat diet was significantly reduced in the mice supplemented with strictinin of 130 mg/kg. Further analysis showed that weight of epididymal fat, but not that of liver or muscle, increased in mice fed with high-fat diet, and the increase of fat was reduced in the mice supplemented with strictinin. Correspondingly, sizes of adipocytes in epididymis were substantially enlarged in mice fed with high-fat diet, and the enlargement of adipocytes was decreased when strictinin was supplemented. Levels of blood triglyceride, cholesterol and glucose were elevated in mice fed with high-fat diet, and these elevated levels were reduced when strictinin was supplemented. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect