Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma

Autor: Weilin Pu, Xiao Shi, Pengcheng Yu, Meiying Zhang, Zhiyan Liu, Licheng Tan, Peizhen Han, Yu Wang, Dongmei Ji, Hualei Gan, Wenjun Wei, Zhongwu Lu, Ning Qu, Jiaqian Hu, Xiaohua Hu, Zaili Luo, Huajun Li, Qinghai Ji, Jiucun Wang, Xiaoming Zhang, Yu-Long Wang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-26343-3
Popis: The characterisation of the papillary thyroid carcinoma (PTC) tumour microenvironment remains crucial. Here, the authors perform single-cell RNA sequencing in 11 patients and identify potential opportunities for the use of immunotherapy and its combination with anti-angiogenic therapy in PTC.
Databáze: Directory of Open Access Journals