Low-dose Perioperative Dexamethasone Improves 24-hour Post-Operative Pain after Anterior Cruciate Ligament Reconstruction
| Autor: | Khatri K, Sidhu G, Jindal S, Bansal D, Goyal D |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Malaysian Orthopaedic Journal, Vol 16, Iss 1, Pp 76-83 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1985-2533 2232-111X |
| DOI: | 10.5704/MOJ.2203.011 |
| Popis: | INTRODUCTION: Post-operative pain following anterior cruciate ligament reconstruction remains an important challenge. Steroids are used in various surgical procedures to decrease post-operative nausea, vomiting and pain. However, only a few studies have reported the effect of systemic administration of steroids in controlling post- operative pain after anterior cruciate ligament surgery. MATERIALS AND METHODS: We have conducted a prospective randomised trial with 109 patients divided into two groups to determine if administration of dexamethasone in the perioperative period improves pain in the post-operative period. The patients were divided into two groups: D, treatment (dexamethasone) and P, control placebo (saline). Patients in the D treatment group were given the first dose of 10mg of intravenous dexamethasone intravenously intra- operatively and the second dose on transferring of the patient to the inpatient department. The patients in the placebo P group, were administered normal saline in the perioperative period in a similar manner. RESULTS: Post-operative pain was significantly less in the dexamethasone group at rest and on walking (p |
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