Identification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse

Autor:	Yan Huang, Hui-Min Liu, Qian-Ying Mao, Li-Ling Wu, Ruo-Lan Xiang, Guang-Yan Yu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Diabetes mellitus Parotid gland Circular RNAs Inflammation response Actin cytoskeleton Biotechnology TP248.13-248.65 Genetics QH426-470
Zdroj:	BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Druh dokumentu:	article
ISSN:	1471-2164
DOI:	10.1186/s12864-024-10290-6
Popis:	Abstract Background Circular RNAs (circRNAs) are a novel kind of non-coding RNAs proved to play crucial roles in the development of multiple diabetic complications. However, their expression and function in diabetes mellitus (DM)-impaired salivary glands are unknown. Results By using microarray technology, 663 upregulated and 999 downregulated circRNAs companied with 813 upregulated and 525 downregulated mRNAs were identified in the parotid glands (PGs) of type2 DM mice under a 2-fold change and P
Databáze:	Directory of Open Access Journals
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