| Autor: |
Mohammad Amiri, Reza Gerami, Babak Shekarchi, Amirreza Azimi, Bahador Asadi, Hamed Bagheri |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
European Journal of Radiology Open, Vol 10, Iss , Pp 100465- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2352-0477 |
| DOI: |
10.1016/j.ejro.2022.100465 |
| Popis: |
Background: Multiple sclerosis (MS) is recognized as the most prevalent autoimmune abnormality of the CNS. T1WI, T2WI, and FLAIR are limited in the quantification of tissue damage and detection of tissue alterations in white and grey matter in MS. This study aimed to the evaluation of changes in DTI indices in these patients at the thalamus and basal ganglia. Methods: 30 relapsing-remitting MS (RRMS) cases and 30 normal individuals were included. Conventional MRI (T2, FLAIR) was acquired to confirm NAGM in MS patients. A T1 MPRAGE protocol was used to normalize DTI images. FSL, SPM, and Explore DTI software were employed to reach Mean Diffusivities (MD), Axial Diffusivities (AD), Fractional anisotropy (FA), and Radial Diffusivity (RD) at the thalamus and the basal ganglia. Results: The FA and RD of the thalamus were decreased in healthy controls compared to MS cases (0.319 vs. 0.296 and 0.0009 vs. 0.0006, respectively) (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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