| Autor: |
Felipe Ferreira, Julia Silva Valério Diniz, Patrícia Medeiros-Souza, Marco Polo Dias Freitas, Einstein Francisco Camargos, Liana Tieko Evangelista Kusano, Leopoldo Luiz dos Santos-Neto |
| Jazyk: |
English<br />Portuguese |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Geriatrics, Gerontology and Aging, Vol 9, Pp 21-25 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2447-2123 |
| Popis: |
OBJECTIVE: To analyse the occurrence of potential high-risk drug-drug interactions in elderly individuals with dementia. METHODS: The sample was chosen from a geriatric outpatient clinic of the Multidisciplinary Center for the Elderly in the University Hospital of Brasília. This cross-sectional study included patients aged 60 or older with a diagnosis of dementia. The prescriptions were analyzed using the Lexi-Interact® database to identify possible potential drug-drug interactions. RESULTS: The study included 97 participants. Sixty-one patients (62.9%) had at least one clinically important potential drug-drug interactions (risks C and D). Of the 264 interactions identified, 23 (8.7%) were classified as risk D, 14 were pharmacodynamics and nine pharmacokinetic. CONCLUSION: The results of this study suggest an increased frequency in the occurrence of clinically significant potential drug-drug interactions in dementia patients. This reinforces the need for drug-drug interaction studies in specific populations. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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