CORRELATION BETWEEN LEFT VENTRICULAR CONTRACTILITY AND MYOCARDIAL T1-RELAXATION TIME DURING MAPPING IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY BY MAGNETIC RESONANCE IMAGING
| Autor: | O. Yu. Dariy, S. A. Aleksandrova, V. S. Bereznitskiy, L. A. Yurpol’skaya, V. N. Makarenko, L. A. Bockeria |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Вестник рентгенологии и радиологии, Vol 99, Iss 2, Pp 71-78 (2018) |
| Druh dokumentu: | article |
| ISSN: | 0042-4676 2619-0478 |
| DOI: | 10.20862/0042-4676-2018-99-2-71-78 |
| Popis: | Objective. To determine a correlation of myocardial deformation with myocardial T1-relaxation time during extracellular volume (ECV) fraction mapping and the degree of focal fibrosis in each left ventricular (LV) segment in patients with hypertrophic cardiomyopathy (HCM). Material and methods. A diagnostic test was carried out in 30 patients diagnosed with HCM and in a control group of 10 patients without LV pathology. Cardiac magnetic resonance imaging was performed on a 3.0 T Philips Achieva TX MRI scanner (Philips, Best, the Netherlands) in accordance of the specialized protocol using a 32-channel cardiac coil with heart rate synchronization and the use of gadolinium-based contrast agents at a dose of 0.3 ml/kg. LV T1 mapping was done using the Modified Look-Locker Inversion Recovery (MOLLI) sequences. Postprocessing was performed on Philips and CVI42 workstations. When the data were processed, T1-relaxation time was estimated before and after contrast enhancement.Results. In all cases, myocardial thickness, extent of myocardial fibrosis, myocardial T1-relaxation time parameters, and ECV could be estimated according to the American Heart Association 16-segment coronary artery model. Before injection of contrast agent, the average LV T1 relaxation time in patients with HCM was 1317±94 msec which was significantly higher than that in the control group (1093±23.7 msec). ECV in the control group was lower (24.8±1.9%) than that in the HCM group (29.8±4.5%). In the univariable group, each index was related to myocardial deformation indicators (radial (Err-FT) and circular (Ecc-FT)) at the segment level. There was a moderate positive correlation between LV thickness and Ecc-FT (r=0.52; p |
| Databáze: | Directory of Open Access Journals |
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