REGIONAL GENOTYPES OF HELICOBACTER PYLORI IN CHILDREN WITH GASTRODUODENAL PATHOLOGY IN THE REPUBLIC OF BASHKORTOSTAN
| Autor: | A. A. Nijevitch, E. N. Akhmadeeva, E. S. Kuchina, M. M. Tuygunov, V. U. Sataev |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Медицинский вестник Юга России, Vol 0, Iss 2, Pp 94-97 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2219-8075 2618-7876 |
| DOI: | 10.21886/2219-8075-2013-2-94-97 |
| Popis: | Purpose: To investigate regional variants of H. pylori genotypes.Materials and methods: Regional variants of H. pylori genotypes have been studied (Cag A, Vac A, Ice A, Bab A2) in clinical strains of H. pylori, obtained from 91 paediatric patients (mean age 14.3±1.6 years), with gastroduodenal pathology in the Republic of Bashkortostan.Results: Marker of pathogenicity island Cag A was revealed in 42 patients (46.1%), Bab A2 – in 31 (34%), Vac A genotype S1 - in 59 (64.8%) and S2 - in 32 (35.2%), Ice A1 - in 72 (79.1%), Ice A2 - in 19 (20.9%).Summary: Among the patients with peptic ulceration, H. pylori strains, carrying markers of pathogenicity island Cag A / Vac AS1 in combination with Bab A2 were detected significantly more often. |
| Databáze: | Directory of Open Access Journals |
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