Exploring psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder

Autor: Jonathan Brett, Elizabeth Knock, P. Todd Korthuis, Paul Liknaitzky, Kevin S. Murnane, Christopher R. Nicholas, James C. Patterson, Christopher S. Stauffer
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Psychiatry, Vol 14 (2023)
Druh dokumentu: article
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2023.1123424
Popis: Methamphetamine use disorder is a chronic relapsing condition associated with substantial mental, physical, and social harms and increasing rates of mortality. Contingency management and psychotherapy interventions are the mainstays of treatment but are modestly effective with high relapse rates, while pharmacological treatments have shown little to no efficacy. Psilocybin-assisted psychotherapy is emerging as a promising treatment for a range of difficult-to-treat conditions, including substance use disorders; however, no studies have yet been published looking at psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder. Here we review the rationale for psilocybin-assisted psychotherapy as a potential treatment for this indication, and describe practical considerations based on our early experience designing and implementing four separate clinical trials of psilocybin-assisted psychotherapy for methamphetamine use disorder.
Databáze: Directory of Open Access Journals