Bacterial Aetiology and Susceptibility of Pathogens Associated with Acne Vulgaris
Autor: | M Deborah Pusushottam, Nasepogu Padmaja, A Venkateshwara Rao |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Journal of Clinical and Diagnostic Research, Vol 15, Iss 10, Pp DC07-DC10 (2021) |
Druh dokumentu: | article |
ISSN: | 2249-782X 0973-709X |
DOI: | 10.7860/JCDR/2021/49350.15512 |
Popis: | Introduction: Acne vulgaris is a pilosebaceous disorder among youth during puberty and also in young adults. Hormonal imbalance, bacterial activity and inflammation can cause acne formation. Due to some anti-inflammatory effects and temporary self treatment of acne using some antibiotics, there is overuse/ improper use of antimicrobial agents which leads to resistance in bacterial strains. Aim: To provide an overview of bacteria that may cause acne and determine their susceptibility to antibiotics and reduce the overuse of antibiotics which leads to antibiotic resistance. Materials and Methods: This was a cross-sectional study done on samples from from 100 patients with chief complaints of acne, attending Dermatology Department at Konaseema Institute of Medical Sciences and Research Foundation (KIMS RF). This study was done between November 2019 to February 2021. Acne pustules were cultured on all the basic media like blood agar and Mac Conkey agar, under aerobic and anaerobic conditions. Bacterial identification was performed by gram staining and relevant biochemical tests. Antibiotic susceptibility was done based on the Clinical and Laboratory Standards Institute (CLSI) 2019. Data was calculated and analysed statistically by Statistical Package for Social Science (SPSS) version 21.0. Results: Total 100 participants were taken for the study. Females (63%) were more commonly affected as compared to males (37%) and the most commonly affected age group was teenage i.e., 10 to 20 years in both male and females. Among 100 subjects, 77 cases showed bacterial growth by aerobic and anaerobic culture and 23 cases showed negative for bacterial culture. All isolates were susceptible to rifampin (100%) (p |
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