The changing role of radiation therapy in the management of oligometastatic disease

Autor: H. Tharmalingham, P.J. Hoskin
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Technical Innovations & Patient Support in Radiation Oncology, Vol 1, Iss , Pp 13-15 (2017)
Druh dokumentu: article
ISSN: 2405-6324
DOI: 10.1016/j.tipsro.2017.01.001
Popis: It is clear from surgical series that there are selected patients presenting with localised metastatic disease who can be cured by radical ablation of the metastasis. To date this has been limited to surgical resection but the evolution of stereotactic ablative body radiotherapy (SABR) has opened new opportunities. Hypofractionated radiation delivery in 1 to 5 fractions can achieve durable local control with low toxicity. The focus is now to develop robust biomarkers so that those with true oligometastatic and thereby potentially curable disease can be selected for this approach. Keywords: Oligometastases, Stereotactic ablative body radiotherapy (SABR), Biomarkers
Databáze: Directory of Open Access Journals