| Autor: |
Jyh-Horng Sheu, Ping-Jyun Sung, Chih-Chung Liaw, Chi-Jen Tai, Jui-Hsin Su, Chiung-Yao Huang, Shwu-Li Wu |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Marine Drugs, Vol 10, Iss 6, Pp 1203-1211 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1660-3397 |
| DOI: |
10.3390/md10061203 |
| Popis: |
Four new eunicellin-based diterpenes, simplexins P–S (1–4), and the known compound simplexin A (5), have been isolated from the soft coral Klyxum simplex. The structures of the new metabolites were determined on the basis of extensive spectroscopic analysis, particularly 1D and 2D NMR experiments. Compounds 1 and 3–5 were shown to exhibit cytotoxicity against a limited panel of cancer cell lines, 3 being the most cytotoxic. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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