The Brain–Heart Link: A Case Report of a Critically Located Multiple Sclerosis Lesion in the Brainstem Leading to Recurrent Takotsubo Syndrome

Autor: Florentijn Risseeuw, Pegah Masrori, Ingrid Baar, Simon Nicolay, Constantijn Franssen, Barbara Willekens
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Druh dokumentu: article
ISSN: 2297-055X
DOI: 10.3389/fcvm.2021.674118
Popis: Various central nervous system (CNS) diseases, including neurovascular and neuroinflammatory diseases, can lead to stress cardiomyopathy, also known as Takotsubo syndrome (TTS). We present a case of a 69-year-old woman with cardiovascular comorbidities, suffering from repeated episodes of TTS and respiratory failure due to a critical lesion in the brainstem, leading to a diagnosis of multiple sclerosis (MS). Despite aggressive treatment, intractable and recurrent symptoms in our patient occurred. Repeated bouts of autonomic dysfunction and respiratory failure ultimately led to installment of palliative care and the patient passing away. TTS should raise suspicion for underlying neurological diseases. Thorough questioning of previous neurological symptoms and extensive neurological workup is warranted. MS should be considered as a trigger of TTS also in elderly patients with cardiovascular risk factors.
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