| Autor: |
Mutlu Sahin, Erkan Ozturk, Mehmet Fatih Can, Ismail Hakki Ozerhan, Gokhan Yagci, Belma Aslim |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Van Tıp Dergisi, Vol 27, Iss 4, Pp 388-396 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2587-0351 |
| DOI: |
10.5505/vtd.2020.92979 |
| Popis: |
INTRODUCTION: Aim of this study was to determine the second phase changes that may occur after a splenectomy; when probiotics, with proven therapeutic effects of intestinal mucosal immunity and systemic immunity, are utilized. METHODS: Total of 56 female Sprague-Dawley rats were used and divided into eight groups. Low exopolysaccharide (EPS) producing Lactobacillus delbrueckii subspecies bulgaricus A13 strain, or high EPS producing Lactobacillus delbrueckii subspecies bulgaricus B3 strain, was orally applied to the rats pre-operatively or post-operatively. Splenectomy was performed on the 8th day of the study and cardiac blood sampling and small bowel resection were performed on the 16th day. RESULTS: In terms of systemic immunity assay whilst there was no significant difference found between IL-6 and IL-10, a significant difference was detected between the groups in TNF-α, TGF-β, IL-4, IL-12 and IL-12 / IL-4 statistical comparisons (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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