Mycoplasma pneumoniae infection and macrolide resistance of children hospitalized in Ningbo Area, Zhejiang Province in 2019‒2021

Autor: LIU Xin
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Shanghai yufang yixue, Vol 35, Iss 2, Pp 154-158 (2023)
Druh dokumentu: article
ISSN: 1004-9231
DOI: 10.19428/j.cnki.sjpm.2023.22277
Popis: ObjectiveTo investigate Mycoplasma pneumoniae (MP) infection and macrolide resistance of hospitalized children in Ningbo Area in 2019‒2021.MethodsA total of 6 782 respiratory throat swab specimens were collected from hospitalized pediatric patients with pneumoniae, admitted in Ningbo Women and Children's Hospital from January, 2019 to December 2021. MP and its mutations in 23S rRNA were detected by real-time polymerase chain reaction.ResultsAmong 6 782 respiratory throat swab specimens from 2019‒2021, 1 290 cases (19.02%) were MP positive, and the positive rate decreased year by year (P0.05), respectively. The difference of positive rate among the different age was significant (P0.05).ConclusionThe infection rate of MP in children decreases in Ningbo Area from 2019 to 2021. MP infection may be related with gender, seasonal distribution, age, and the resistance rate of MP to macrolide is high.
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