Proteomic patterns in glomerular research, a laser capture microdissection and liquid chromatography-tandem mass spectrometry approach

Autor: Bărar Andrada A., Pralea Ioana E., Berindan-Neagoe Ioana, Pirlog Radu, Nutu Andreea, Maslyennikov Yuriy, Potra Alina R., Iuga Cristina A., Kacso Ina M.
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Romanian Journal of Laboratory Medicine, Vol 31, Iss 4, Pp 263-274 (2023)
Druh dokumentu: article
ISSN: 2284-5623
DOI: 10.2478/rrlm-2023-0029
Popis: Introduction: Molecular techniques have the potential to shed light on glomerular diseases that conventional renal pathology may be unable to reveal. The aim of this study was to investigate whether proteomic patterns of glomeruli obtained from kidney biopsies can differentiate between minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS) and control groups (CTR).
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