| Autor: |
Johannes M. Wirkus, Fabienne Goss, Matthias David, Erik K. Hartmann, Kimiko Fukui, Irene Schmidtmann, Eva Wittenmeier, Gunther J. Pestel, Eva-Verena Griemert |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
BJA Open, Vol 11, Iss , Pp 100291- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2772-6096 |
| DOI: |
10.1016/j.bjao.2024.100291 |
| Popis: |
Background: Pulse wave transit time (PWTT) shows promise for monitoring intravascular fluid status intraoperatively. Presently, it is unknown how PWTT mirrors haemodynamic variables representing preload, inotropy, or afterload. Methods: PWTT was measured continuously in 24 adult volunteers. Stroke volume was assessed by transthoracic echocardiography. Volunteers underwent four randomly assigned manoeuvres: ‘Stand-up’ (decrease in preload), passive leg raise (increase in preload), a ‘step-test’ (adrenergic stimulation), and a ‘Valsalva manoeuvre’ (increase in intrathoracic pressure). Haemodynamic measurements were performed before and 1 and 5 min after completion of each manoeuvre. Correlations between PWTT and stroke volume were analysed using the Pearson correlation coefficient. Results: ‘Stand-up’ caused an immediate increase in PWTT (mean change +55.9 ms, P-value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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