Antitumorigenic activity of the herbal mixture-ak27 on ehrlich ascites carcinoma in mice

Autor: İbrahim DEMİRKAN, Tolga ERTEKİN, Musa KORKMAZ, İbrahim KILIÇ, Aysun ÇEVİK-DEMİRKAN, Fatih BOZKURT, Ahmet KONUKTÜRK
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Kafkas Universitesi Veteriner Fakültesi Dergisi, Vol 23, Iss 5, Pp 817-823 (2017)
Druh dokumentu: article
ISSN: 1309-2251
DOI: 10.9775/kvfd.2017.17971
Popis: The treatment of cancer is highly challenging and contains surgery, chemotherapy and radiotherapy alone or combinations which have various side effects on the patient health. This study aimed at observing the possible antineoplastic activity of AK27-herbal mixture, a combination of pistachio resin, rhus resin, pollen, N. sativa seed, pomegranate skin and olive oil, on experimentally induced Ehrlich ascites carcinoma (EAC) in a mouse model. EAC-bearing mice were evaluated by tumor cell count (viable and non-viable), median survival time, percentage increase in the life span and live body weight changes up to 30 days of EAC inoculation. Volume of EAC cells and viable cell count were found to be significantly decreased in AK27 treated groups when compared to EAC control group (P
Databáze: Directory of Open Access Journals