COVID-19 vaccine acceptance and perceived stigma in patients with depression: a network perspective

Autor: Hong Cai, Wei Bai, Xiangdong Du, Ling Zhang, Lan Zhang, Yu-Chen Li, Huan-Zhong Liu, Yi-Lang Tang, Todd Jackson, Teris Cheung, Feng-Rong An, Yu-Tao Xiang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2158-3188
DOI: 10.1038/s41398-022-02170-y
Popis: Abstract The association between coronavirus disease (COVID-19) vaccine acceptance and perceived stigma of having a mental illness is not clear. This study examined the association between COVID-19 vaccine acceptance and perceived stigma among patients with recurrent depressive disorder (depression hereafter) using network analysis. Participants were 1149 depressed patients (842 men, 307 women) who completed survey measures of perceived stigma and COVID-19 vaccine attitudes. T-tests, chi-square tests, and Kruskal–Wallis tests were used to compare differences in demographic and clinical characteristics between depressed patients who indented to accepted vaccines and those who were hesitant. Hierarchical multiple regression analyses assessed the unique association between COVID-19 vaccine acceptance and perceived stigma, independent of depression severity. Network analysis examined item-level relations between COVID-19 vaccine acceptance and perceived stigma after controlling for depressive symptoms. Altogether, 617 depressed patients (53.7%, 95 confidence intervals (CI) %: 50.82–56.58%) reported they would accept future COVID-19 vaccination. Hierarchical multiple regression analyses indicated higher perceived stigma scores predicted lower levels of COVID-19 vaccination acceptance (β = −0.125, P
Databáze: Directory of Open Access Journals