| Autor: |
JIA Zi-qi, WANG Yan-yu, WANG Ya-dong, BING Zhong-xing, LIANG Nai-xin, LI Shan-qing |
| Jazyk: |
čínština |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Jichu yixue yu linchuang, Vol 40, Iss 8, Pp 1130-1134 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1001-6325 |
| Popis: |
Lung cancer has high morbidity and mortality rate. Thus, an efficient pre-clinical model that can serve the translational study is urgently needed. The application of organoid should be compared to existing in vitro and in vivo models under different circumstances. The development of organoids of lung cancer has undergone three stages as tissue-specific stem cell differentiation, mixed cell manipulation, and 2-dimensional cultivation. Now, lung cancer organoid can be developed from samples harvested through surgery, biopsy, and circulating tumor cells, with a wide range of application. This review aims to summarize the historical development and application of lung cancer organoids. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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