Clinical response in metastatic castration‐resistant prostate cancer (mCRPC) cases treated with supra‐physiological doses of testosterone: Bipolar androgen therapy

Autor: Senji Hoshi, Vladimir Bilim, Kiyotsugu Hoshi, Takuya Nakagawa, Sadanobu Sato, Rie Sakagami, Masato Konno, Takashi Kudo, Kenji Numahata, Isoji Sasagawa
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Clinical Case Reports, Vol 10, Iss 2, Pp n/a-n/a (2022)
Druh dokumentu: article
ISSN: 2050-0904
DOI: 10.1002/ccr3.5433
Popis: Abstract Androgen deprivation therapy is a standard of care for metastatic prostate cancer. A paradoxical approach utilizing high doses of testosterone in castration‐resistant prostate cancer patients demonstrated clinical responses. Here, we report on four heavily pretreated Japanese patients (including one patient on hemodialysis) successfully treated with supra‐physiological doses of testosterone.
Databáze: Directory of Open Access Journals
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