Autor: |
Chunmeng Ding, Yuexing Zhu, Zhiyuan Huo, Shouzhi Yang, Yan Zhou, Ayizekeranmu Yiming, Wei Chen, Shanrong Liu, Kun Qian, Lin Huang |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Materials Today Bio, Vol 26, Iss , Pp 101047- (2024) |
Druh dokumentu: |
article |
ISSN: |
2590-0064 |
DOI: |
10.1016/j.mtbio.2024.101047 |
Popis: |
Polyphenols with antioxidant properties are of significant interest in medical and pharmaceutical applications. Given the diverse range of activities of polyphenols in vivo, accurate detection of these compounds plays a crucial role in nutritional surveillance and pharmaceutical development. Yet, the efficient quantitation of polyphenol contents and qualification of monomer compositions present a notable challenge when studying polyphenol bioavailability. In this study, platinum-modified nickel-iron layered double hydroxide (Pt/NiFe-LDH hybrids) were designed to mimic peroxidases for colorimetric analysis and act as enhanced matrices for laser desorption/ionization mass spectrometry (LDI MS) to quantify and qualify polyphenols. The hybrids exhibited an enzymatic activity of 33.472 U/mg for colorimetric assays, facilitating the rapid and direct quantitation of total tea polyphenols within approximately 1 min. Additionally, the heterogeneous structure and exposed hydroxyl groups on the hybrid surface contributed to photoelectric enhancement and in-situ enrichment of polyphenols in LDI MS. This study introduces an innovative approach to detect polyphenols using advanced materials, potentially inspiring the future development and applications of other photoactive nanomaterials. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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