Onset of Type I Diabetes Followed by Scleroderma Syndrome in a Child After the COVID-19: A Case Report

Autor: Ievgeniia Burlaka PhD, Inga Mityuryayeva PhD, Olena Sevastiian MD, Ivanna Kachula MD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Global Pediatric Health, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2333-794X
2333794X
DOI: 10.1177/2333794X241276356
Popis: Morphea, is a chronic inflammatory disease of the dermis and subcutaneous tissue. Research has indicated a connection between morphea and Type I Diabetes (T1D). COVID-19 can cause autoimmune diseases like scleroderma, T1D, systemic lupus erythematosus, and others. A 12-year-old girl with type 1 diabetes who was on insulin therapy was brought into the clinic for a metabolic evaluation. The patient had induration, skin hardness, and cutaneous erythema upon inspection. The onset of T1D was following a mild COVID-19 infection. Signs of morphea merged 3 months after the onset of T1D. Known as “long-term COVID,” this sickness phase that follows the acute stage of COVID-19 is most likely the result of autoimmune activation. As this patient under evaluation reveals, COVID-19 has been demonstrated in the literature to cause the production of autoantibodies and to either cause or worsen autoimmune disorders in people who have a genetic susceptibility.
Databáze: Directory of Open Access Journals