Exacerbation of psychotic symptoms as clinical presentation of Wernicke encephalopathy in an Alzheimer's disease patient

Autor: Nozomu Uchida, Mayumi Ishida, Izumi Sato, Takao Takahashi, Daisuke Furuya, Yasuhiro Ebihara, Hiroshi Ito, Akira Yoshioka, Hideki Onishi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of General and Family Medicine, Vol 21, Iss 5, Pp 185-187 (2020)
Druh dokumentu: article
ISSN: 2189-7948
DOI: 10.1002/jgf2.330
Popis: Abstract Although there have been recent reports of nonalcoholic thiamine deficiency (TD), no association has been reported between the exacerbation of the psychiatric symptoms of Alzheimer's disease patient and TD. An 89‐year‐old woman with dementia visited our hospital because of acute deterioration in behavioral and psychological symptoms of dementia (BPSD). Her medical history revealed a decrease in oral food intake lasting more than 2 weeks, so that TD was suspected and abnormal behavior improved significantly after thiamine administration. Thiamine deficiency should be suspected in patients with dementia who demonstrate acute deterioration in BPSD possibly related to poor oral food intake.
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