Effects of Aqueous Stem Extract of Massularia Acuminata on Some Liver Function Indices of Male Rats
| Autor: | Musa Toyin Yakubu, Babasoji Percy Omoniwa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Iranian Journal of Toxicology, Vol 6, Iss 18, Pp 716-722 (2012) |
| Druh dokumentu: | article |
| ISSN: | 2008-2967 2251-9459 |
| Popis: | Background: Massularia acuminata has been claimed to be used in managingseveral ailments in folk medicine and in some instances substantiated withscientific data. This however has been without recourse to its safety. Therefore,aqueous stem extract of M. acuminata was evaluated for its effects on somefunction indices of the liver of male rats.Methods: Sixty, male rats were grouped into 4 (A, B, C and D) such that Group A(control) was orally administered 1cm3 of distilled water while those in groups B, Cand D received orally 1 cm3 of extract corresponding to 250, 500 and 1000 mg/kgbody weight respectively. Some biochemical parameters of liver function wereevaluated in the animals after 1, 7 and 21 daily doses.Results: The extract significantly decreased (P |
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