Surveying silicon nitride nanopores for glycomics and heparin quality assurance

Autor: Buddini Iroshika Karawdeniya, Y. M. Nuwan D. Y. Bandara, Jonathan W. Nichols, Robert B. Chevalier, Jason R. Dwyer
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-05751-y
Popis: The complexity of polysaccharides significantly complicates their analysis in comparison to other biopolymers. Here, the authors demonstrate that solid-state silicon nitride nanopore sensors can be used to reliably detect native polysaccharides and to perform a simple quality assurance assay on a polysaccharide therapeutic, heparin.
Databáze: Directory of Open Access Journals