| Autor: |
Craig E. Grossman, MD, PhD, MSCE, Michael R. Folkert, MD, Stephanie Lobaugh, MS, Neil B. Desai, MD, MHS, Marisa A. Kollmeier, MD, Daniel Gorovets, MD, Sean M. McBride, MD, MPH, Robert D. Timmerman, MD, Zhigang Zhang, PhD, Michael J. Zelefsky, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Advances in Radiation Oncology, Vol 8, Iss 4, Pp 101070- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2452-1094 |
| DOI: |
10.1016/j.adro.2022.101070 |
| Popis: |
Purpose: Although hydrogel spacer placement (HSP) minimizes rectal dose during prostate cancer radiation therapy, its potential benefit for modulating rectal toxicity could depend on the achieved prostate-rectal separation. We therefore developed a quality metric associated with rectal dose reduction and late rectal toxicity among patients treated with prostate stereotactic body radiation therapy (SBRT). Methods and Materials: A quality metric consisting of prostate-rectal interspace measurements from axial T2-weighted magnetic resonance imaging simulation images was applied to 42 men enrolled in a multi-institutional phase 2 study using HSP with prostate SBRT (45 Gy in 5 fractions). A score of 0, 1, or 2 was assigned to a prostate-rectal interspace measurement of |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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