Autor: |
Iryna Nikitina, Volodymyr Boiko, Tetiana Babar, Natalia Kalashnik, Nataliia Ikonopistseva, Alesia Boiko, Maryna Bolotna |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
|
Zdroj: |
Galician Medical Journal, Vol 27, Iss 1, Pp E202016-E202016 (2020) |
Druh dokumentu: |
article |
ISSN: |
2414-1518 |
DOI: |
10.21802/gmj.2020.1.6 |
Popis: |
To assess the role of the placental growth factor in the development of gestational complications during multiple pregnancy, there was conducted a study of this indicator in serum of 320 pregnant women with multiple pregnancy in the first trimester and 40 pregnant women with singleton pregnancy (the control group). The objective of the research was to study the effect of placental growth factors on the gestational process in multiple pregnancy. Materials and Methods. There was conducted a prospective study of pregnancy and childbirth in 320 females with multiple pregnancy (the main group) and 40 healthy women with singleton pregnancy. The level of serum placental growth factor was determined by enzyme-linked immunosorbent assay using monoclonal antibodies in the first trimester of pregnancy. The indicators of the hemostasis system (vascular, platelet and coagulation components) were evaluated according to generally accepted methods. Doppler ultrasound of the placental and fetal blood flow was performed in the uterine arteries, the umbilical artery and vein, the fetal middle cerebral artery. Results. Women with multiple pregnancy were at high risk of developing gestational complications such as preterm deliveries (67.8%, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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