A genome-wide association study of contralateral breast cancer in the Women’s Environmental Cancer and Radiation Epidemiology Study

Autor:	Xiaohui Sun, Anne S. Reiner, Anh Phong Tran, Gordon P. Watt, Jung Hun Oh, Lene Mellemkjær, Charles F. Lynch, Julia A. Knight, Esther M. John, Kathleen E. Malone, Xiaolin Liang, Meghan Woods, Andriy Derkach, Patrick Concannon, Jonine L. Bernstein, Xiang Shu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Contralateral breast cancer Genetic factors Genome-wide association study Polygenic risk score Chemotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Breast Cancer Research, Vol 26, Iss 1, Pp 1-7 (2024)
Druh dokumentu:	article
ISSN:	1465-542X
DOI:	10.1186/s13058-024-01765-1
Popis:	Abstract Background Contralateral breast cancer (CBC) is the most common second primary cancer diagnosed in breast cancer survivors, yet the understanding of the genetic susceptibility of CBC, particularly with respect to common variants, remains incomplete. This study aimed to investigate the genetic basis of CBC to better understand this malignancy. Findings We performed a genome-wide association analysis in the Women’s Environmental Cancer and Radiation Epidemiology (WECARE) Study of women with first breast cancer diagnosed at age
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/c326165dc5464d9caba6fbd5ced243de Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ