Identifying the Risk Factors of Early Neurological Deterioration After Thrombolysis in Patients with Acute Ischemic Stroke

Autor: Yasemin Dinç, Rıfat Özpar, Bahattin Hakyemez, Mustafa Bakar
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Türk Nöroloji Dergisi, Vol 28, Iss 3, Pp 176-181 (2022)
Druh dokumentu: article
ISSN: 1309-2545
93548788
DOI: 10.4274/tnd.2022.55531
Popis: Objective: The efficacy of intravenous (IV) recombinant tissue plasminogen activator (rt-PA) therapy in the treatment of acute ischemic stroke (AIS) has been demonstrated in many studies and IV rt-PA therapy has been increasingly used all over the world. Early neurological deterioration (END) in AIS is common and potentially associated with a poor clinical outcome. The prevalence of END in AIS ranges from 13% to 37% in studies. The aim of this study is to determine the prevalence and risk factors of END in patients with AIS receiving IV rt-PA therapy. Materials and Methods: One hundred fifty seven patients who were given IV rt-PA treatment by Bursa Uludag University Faculty of Medicine, Department of Neurology between 01.01.2020 and 01.01.2021 were retrospectively included in this study. It was planned to determine the risk group by comparing patients with END with those without. Results: Age (p=0.023), serum glucose level (p=0.045), The National Institutes of Health Stroke score at discharge (p
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