Effects of Dietary Nitrate Supplementation on Performance during Single and Repeated Bouts of Short-Duration High-Intensity Exercise: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

Autor: Nehal S. Alsharif, Tom Clifford, Abrar Alhebshi, Samantha N. Rowland, Stephen J. Bailey
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Antioxidants, Vol 12, Iss 6, p 1194 (2023)
Druh dokumentu: article
ISSN: 2076-3921
DOI: 10.3390/antiox12061194
Popis: Inorganic nitrate (NO3−) has emerged as a potential ergogenic aid over the last couple of decades. While recent systematic reviews and meta-analyses have suggested some small positive effects of NO3− supplementation on performance across a range of exercise tasks, the effect of NO3− supplementation on performance during single and repeated bouts of short-duration, high-intensity exercise is unclear. This review was conducted following PRISMA guidelines. MEDLINE and SPORTDiscus were searched from inception to January 2023. A paired analysis model for cross-over trials was incorporated to perform a random effects meta-analysis for each performance outcome and to generate standardized mean differences (SMD) between the NO3− and placebo supplementation conditions. The systematic review and meta-analysis included 27 and 23 studies, respectively. Time to reach peak power (SMD: 0.75, p = 0.02), mean power output (SMD: 0.20, p = 0.02), and total distance covered in the Yo-Yo intermittent recovery level 1 test (SMD: 0.17, p < 0.0001) were all improved after NO3− supplementation. Dietary NO3− supplementation had small positive effects on some performance outcomes during single and repeated bouts of high-intensity exercise. Therefore, athletes competing in sports requiring single or repeated bouts of high-intensity exercise may benefit from NO3− supplementation.
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