From Keratoma to Anaplastic Malignant Melanoma in a Horse’s Hoof

Autor: Elżbieta Stefanik, Kamil Górski, Bernard Turek, Olga Drewnowska-Szczepakowska, Katarzyna Kliczkowska-Klarowicz, Aleksandra Stefanik
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Animals, Vol 12, Iss 22, p 3090 (2022)
Druh dokumentu: article
ISSN: 2076-2615
DOI: 10.3390/ani12223090
Popis: Melanomas in horses are most often associated with gray, older horses with an average age of over 16 years. Anaplastic malignant melanoma, however, can very rarely affect non-gray horses. Herein, we report a case of a 16-year-old Wielkopolski gelding with a chronic lameness caused by a mass in the hoof. The first resection of the lesion and histopathological examination confirmed the presence of a keratoma. The regrown mass and persistent lameness resulted in another mass resection. The second histopathological examination result suggested a neoplastic growth of melanocytic origin with a low histological malignancy. Less than 2 years after the first resection, the horse returned to the clinic with deformation of the hoof capsule and severe lameness. The result of the third histopathological examination indicated low-differentiated malignant neoplasm. The result of the immunohistochemically test indicates a tumor of melanocytic origin with high malignancy.
Databáze: Directory of Open Access Journals
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