Contrast microsphere enhancement of the tricuspid regurgitant spectral Doppler signal - Is it still necessary with contemporary scanners?

Autor: David G. Platts, Manan Vaishnav, Darryl J. Burstow, Christian Hamilton Craig, Jonathan Chan, John F. Sedgwick, Gregory M. Scalia
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 17, Iss C, Pp 1-10 (2017)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2017.08.002
Popis: Background: Accurate evaluation of the tricuspid regurgitant (TR) spectral Doppler signal is important during transthoracic echocardiographic (TTE) evaluation for pulmonary hypertension (PHT). Contrast enhancement improves Doppler backscatter. However, its incremental benefit with contemporary scanners is less well established. The aim of this study was to assess whether the TR spectral Doppler signal using contemporary scanners was improved using a second generation contrast agent, Definity® (CE), compared to unenhanced TTE (UE). Methods: Analysis of patients who underwent UE then CE TR interrogation was performed. TR signal was evaluated by an experienced reader and graded 1 (clear-high level of confidence of interpretation and complete spectral Doppler envelope), 2 (suboptimal with medium-low level of confidence of interpretation and incomplete envelope), 3 (poor-absent and no measurable spectral Doppler signal). Maximal TR velocity (TRV) was defined as peak velocity that could be clearly identified. An inexperienced sonographer read 30 randomly selected studies. Results: 176 TTE were performed in 173 patients (mean age 57 ± 14.8 years). Wilcoxon signed rank test demonstrated significant improvement (p
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