Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages

Autor: Heung Sik Hahm, Mattan Hurevich, Peter H Seeberger
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms12482
Popis: Automated glycan assembly has proven a powerful method to rapidly synthesize large oligosaccharides, though stereoselective cis-glycosylation remains a challenge. Here, the authors demonstrate a system to selectively incorporate multiple cis-glycosidic linkages by use of remote participating groups.
Databáze: Directory of Open Access Journals