Phosphatidic acid production regulated by receptors with liganddependent tyrosine kinase activity

Autor:	Fco. J. G. Muriana, V. Ruiz-Gutiérrez
Jazyk:	English<br />Spanish; Castilian
Rok vydání:	1995
Předmět:	diacylglycerol kinase information (paper) ptiospfiatidic acid phospholipase d recepto tyrosine kinase activity Nutrition. Foods and food supply TX341-641
Zdroj:	Grasas y Aceites, Vol 46, Iss 1, Pp 45-50 (1995)
Druh dokumentu:	article
ISSN:	0017-3495 1988-4214
DOI:	10.3989/gya.1995.v46.i1.902
Popis:	The present study deals with the most recent and important studies on the relationship between transmembrane receptors with ligand-dependent tyrosine kinase activity and cellular lipid metabolism, predominantly in generating phosphatidic acid (PA) as a lipid messenger. The signaling function of phosphatidylcholine hydrolysis and diacylglycerol (DG) phosphorylation by phospholipase D and diacylglycerol kinase, respectively, as different sources for PA is also described. PA may play a role in signal transduction as a putative first or second messenger, and acts to reduce levels of DG and to produce bis-PA by phospholipase D - mediated transphosphatidylation.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/32283f14046b46e48d7f9b4743af10c1 Zobrazit plný text záznamu View record in DOAJ