Coronary artery calcium score: we know where we are but not where we may be

Autor: Giulia Mattesi, Maria Teresa Savo, Morena De Amicis, Filippo Amato, Elena Cozza, Simone Corradin, Stefano Da Pozzo, Marco Previtero, Riccardo Bariani, Giorgio De Conti, Ilaria Rigato, Valeria Pergola, Raffaella Motta
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Monaldi Archives for Chest Disease (2023)
Druh dokumentu: article
ISSN: 1122-0643
2532-5264
DOI: 10.4081/monaldi.2023.2720
Popis: Cardiac computed tomography angiography (CCTA) has emerged as a cost-effective and time-saving technique for excluding coronary artery disease. One valuable tool obtained by CCTA is the coronary artery calcium (CAC) score. The use of CAC scoring has shown promise in risk assessment and stratification of cardiovascular disease. CAC scores can be complemented by plaque analysis to assess vulnerable plaque characteristics and further refine risk assessment. This paper aims to provide a comprehensive understanding of the value of the CAC as a prognostic tool and its implications for patient risk assessment, treatment strategies and outcomes. CAC scoring has demonstrated superior ability in stratifying patients, especially asymptomatic individuals, compared to traditional risk factors and scoring systems. The main evidence suggests that individuals with a CAC score of 0 had a good long-term prognosis, while elevated CAC score is associated with increased cardiovascular risk. Finally, the clinical power of CAC scoring and the develop of new models for risk stratification could be enhanced by machine learning algorithms.
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