Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis

Autor: S. Khan, C. Urban, V. Singh, D. Liu, S. Segal-Maurer, Y. Parmar, J. Yoon
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: IDCases, Vol 24, Iss , Pp e01082- (2021)
Druh dokumentu: article
ISSN: 2214-2509
DOI: 10.1016/j.idcr.2021.e01082
Popis: Granulicatella adiacens, a nutritionally variant streptococci (NVS) is a well described organism associated with endocarditis. Previously communicated cases have documented the use of double beta-lactam therapy with ampicillin and ceftriaxone to treat patients with infective endocarditis due to Enterococcus faecalis and Streptocossus pneumoniae. We describe the first case of Granulicatella adiacens infective endocarditis in a patient successfully treated with the combination of intravenous ampicillin and ceftriaxone and document their synergistic activity.
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