A Case of Intestinal Mastocytosis Misdiagnosed as Crohn's Disease

Autor: Stefania Reggiani, Loretta Cosso, Alessandro Adriani, Stefano Pantaleoni, Alessandro Risso, Federico Vittone, Luigi Chiusa, Nicoletta Sapone, Marco Astegiano
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Case Reports in Gastroenterology, Vol 9, Iss 2, Pp 188-193 (2015)
Druh dokumentu: article
ISSN: 1662-0631
48574112
DOI: 10.1159/000430946
Popis: Systemic mastocytosis (SM) is a rare, heterogeneous and progressive disease, characterized by the accumulation of atypical mast cells in various organs, including the gastrointestinal tract. Gastrointestinal symptoms are present in up to 80% of patients with SM, the most common being abdominal pain, diarrhea, nausea and vomiting. Up to 50% of patients with SM do not have classical skin lesions at presentation, and in these patients the diagnosis of SM can be difficult for years. Here we report a case of SM that initially mimicked inflammatory bowel disease, although the patient showed poor response to steroid therapy. The right diagnosis was made only on the surgical specimen obtained after emergency surgery for intestinal obstruction. SM should therefore be considered in the diagnostic approach in patients with gastrointestinal symptoms not attributable to other pathologies and in cases of suspected inflammatory bowel disease with unusual course.
Databáze: Directory of Open Access Journals
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