Rostral Intralaminar Thalamus Engagement in Cognition and Behavior

Autor: Kara K. Cover, Brian N. Mathur
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Druh dokumentu: article
ISSN: 1662-5153
DOI: 10.3389/fnbeh.2021.652764
Popis: The thalamic rostral intralaminar nuclei (rILN) are a contiguous band of neurons that include the central medial, paracentral, and central lateral nuclei. The rILN differ from both thalamic relay nuclei, such as the lateral geniculate nucleus, and caudal intralaminar nuclei, such as the parafascicular nucleus, in afferent and efferent connectivity as well as physiological and synaptic properties. rILN activity is associated with a range of neural functions and behaviors, including arousal, pain, executive function, and action control. Here, we review this evidence supporting a role for the rILN in integrating arousal, executive and motor feedback information. In light of rILN projections out to the striatum, amygdala, and sensory as well as executive cortices, we propose that such a function enables the rILN to modulate cognitive and motor resources to meet task-dependent behavioral engagement demands.
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