Instrumented cervical fusion using patient specific end-plate conforming interbody devices with a micro-porous structure in nine dogs with disk-associated cervical spondylomyelopathy

Autor: Colin J. Driver, Victor Lopez, Ben Walton, Dan Jones, Rory Fentem, Andrew Tomlinson, Jeremy Rose
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Veterinary Science, Vol 10 (2023)
Druh dokumentu: article
ISSN: 2297-1769
DOI: 10.3389/fvets.2023.1208593
Popis: ObjectiveTo report the medium and long-term outcome of nine dogs with disk-associated cervical spondylomyelopathy (DA-CSM), treated by instrumented interbody fusion using patient specific end-plate conforming device that features a micro-porous structure to facilitate bone in-growth.Study designA retrospective clinical study.AnimalsNine medium and large breed dogs.MethodsMedical records at two institutions were reviewed between January 2020 and 2023. Following magnetic resonance imaging (MRI) diagnosis of DA-CSM, pre-operative computed tomography (CT) scans were exported to computer software for in-silico surgical planning. Interbody devices were 3D-manufactured by selecting laser melting in titanium alloy. These were surgically implanted at 13 segments alongside mono-or bi-cortical vertebral stabilization systems. Follow-up included neurologic scoring and CT scans post-operative, at medium-term follow up and at long-term follow-up where possible. Interbody fusion and implant subsidence were evaluated from follow-up CT scans.ResultsNine dogs were diagnosed with DA-CSM between C5-C7 at a total of 13 operated segments. Medium-term follow up was obtained between 2 and 8 months post-operative (3.00 ± 1.82 months). Neurologic scoring improved (p = 0.009) in eight of nine dogs. Distraction was significant (p
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