| Autor: |
Najla M. El-Barasi, Miloud M. Miloud, Marei M. El-ajaily, Ranjan K. Mohapatra, Ashish K. Sarangi, Debadutta Das, Ahmed Mahal, Pankaj K. Parhi, Lucia Pintilie, Soumya R. Barik, Md. Nur Amin Bitu, Md. Kudrat-E-Zahan, Zishan Tabassum, Saud I. Al-Resayes, Mohammad Azam |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Journal of Saudi Chemical Society, Vol 24, Iss 6, Pp 492-503 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1319-6103 |
| DOI: |
10.1016/j.jscs.2020.04.005 |
| Popis: |
A novel series of three trivalent mononuclear ternary complexes of the type, [ML1L2] [M = Cr(III), Fe(III) and La(III), HL1 = 2-((2-(2,4-dinitrophenyl)hydrazone)methyl)phenol, HL2 = 2-aminophenol] was investigated by various physio-chemical studies. To obtain additional information inside the structure, density functional theory calculation was also carried out. The synthesized complexes showed remarkable antimicrobial activity when tested against A. niger, A. flavus, R. stolonifer, C. albicans, E. coli and Klebsiella sp. microbes. Furthermore, the molecular docking analysis was also carried out to analyze the interactions in protein–ligand complexes. Moreover, the quantitative structure–activity relationship was also investigated to study the biological activity of the ligand. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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