Experience of using multielectrode catheter systems to perform radiofrequency renal sympathetic denervation in patients with resistant hypertension: immediate procedural effects

Autor: M. V. Ionov, I. V. Emelyanov, A. D. Vakhrushev, A. S. Alieva, N. G. Avdonina, Yu. S. Yudina, D. S. Lebedev, Е. N. Mikhailov, A. O. Konradi
Jazyk: ruština
Rok vydání: 2022
Předmět:
Zdroj: Российский кардиологический журнал, Vol 27, Iss 2 (2022)
Druh dokumentu: article
ISSN: 1560-4071
2618-7620
DOI: 10.15829/1560-4071-2022-4794
Popis: Aim. To investigate the baseline characteristics of patients with resistant hypertension (HTN) undergoing radiofrequency renal sympathetic denervation (RD) and to determine immediate procedural effects.Material and methods. During 2018-2019, two series of radiofrequency RD procedures were performed in patients with true resistant HTN using balloon-type (bipolar ablation) or spiral-type (unipolar ablation) multielectorde catheters. The basic demographic, clinical and laboratory characteristics of included patients were assessed. A comparative analysis of two groups was carried out depending on the type of catheter used. Dynamics of office systolic blood pressure (SBP) were assessed as ∆ between the two following timepoints: at screening and at hospital discharge. The safety of radiofrequency RD was assessed. Multiple linear regression was used to determine the factors associated with the ∆ of office SBP after radiofrequency RD.Results. A total of 48 patients taking 4 (4;6) antihypertensive drugs were sequentially included. Radiofrequency RD was performed with a balloon-type catheter in 27 patients (mean age, 56±12 years old; 12 males) and with a spiral-type catheter in 21 patients (50±14 years old; 8 males). Radiofrequency RD was significantly longer in the spiral catheter group than in balloon one (110 versus 60 minutes, p
Databáze: Directory of Open Access Journals