11.1 ENDOTHELIAL FUNCTION IS IMPAIRED IN WOMEN WHO HAD PRE-ECLAMPSIA

Autor: Christian Delles, Catriona Brown, Joanne Flynn, Shona Kerr, David Carty
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Artery Research, Vol 16 (2016)
Druh dokumentu: article
ISSN: 1876-4401
DOI: 10.1016/j.artres.2016.10.089
Popis: Background: Women with a history of pre-eclampsia (PE) are at higher risk of cardiovascular disease later in life. We evaluated the cardiovascular health of women who had PE in comparison with women who had normotensive pregnancies. Methods: We assessed heart rate-adjusted augmentation index (AIx SphygmoCor), carotid-femoral pulse wave velocity (PWV SphygmoCor), carotid intima-media thickness (CIMT ultrasound) and brachial flow-mediated dilatation (FMD ultrasound) in women who were pregnant 1–30 years ago. Results: A total of 166 women (86 cases, 80 controls) attended for vascular studies. Women with a history of PE had higher systolic blood pressure (SBP) (130±14 vs 122±10 mmHg P
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