Neutrophil–lymphocyte ratio and response to plasmapheresis in Guillain–Barré syndrome: a prospective observational study

Autor:	Noha Ali Hashim, Wafaa Samir Mohamed, Engy Mohammed Emad
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Guillain–Barré syndrome Neutrophil–lymphocyte ratio Prognosis Plasmapheresis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 56, Iss 1, Pp 1-6 (2020)
Druh dokumentu:	article
ISSN:	1687-8329
DOI:	10.1186/s41983-020-0154-z
Popis:	Abstract Background Guillain–Barré Syndrome (GBS) is one of the most severe neurological diseases that causes marked disability and even death. Aim The aim of this study is to investigate the role of the neutrophil–lymphocyte ratio (NLR) as a prognostic marker for GBS and response to treatment with plasmapheresis. Methods Seventy-five subjects (35 GBS patients and 40 healthy controls) were recruited. Complete general and neurological examinations were performed and Hughes disability scale score was evaluated for assessing functional motor deficits in GBS patients. In addition, NLR, erythrocyte sedimentation rate, and C-reactive protein level were calculated. Results NLR was significantly higher in GBS patients than in controls (p
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