| Autor: |
Mustafa Vedat Dogru, Celal Bugra Sezen, Volkan Erdogu, Cemal Aker, Abdulsamed Alp, Semih Erduhan, Melek Erk, Aysun Olcmen, Muzaffer Metin |
| Jazyk: |
English<br />Turkish |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Haseki Tıp Bülteni, Vol 59, Iss 3, Pp 221-227 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2147-2688 |
| DOI: |
10.4274/haseki.galenos.2021.6997 |
| Popis: |
Aim:This study aimed to evaluate prognostic factors influencing survival in patients who underwent surgical resection of stage I nonsmall cell lung cancer (NSCLC) in our center.Methods:A total of 472 patients with stage I NSCLC who were operated between January 2007 and November 2018 were retrospectively analyzed in the study. Patient data was collected using hospital database. The remaining patients were divided into 2 groups: patients younger than 65 years of age (group A) and those aged 65 and over (group B).Results:The patient group comprised 80 women (16.9%) and 392 men (83.1%); 152 patients were aged 65 years or over (32.2%) and 320 patients were under 65 years of age (81.5%). The mean follow-up time was 51 months. The 5-year survival rate was 67.2% overall. Patients with stage IA1, IA2, IA3, and IB tumors had 5-year survival of 78.1%, 72.5%, 77.3%, and 56.7%, respectively (p=0.009). In multivariate analysis, advanced age (≥65 years), large cell carcinoma, left-sided surgery, and higher tumor stage were the most important prognostic factors associated with poorer survival.Conclusion:Advanced age was determined to be an independent poor prognostic factor, and sub-group analyses showed that survival outcome was better with tumors smaller than 1 cm. Based on the results of our study, we believe that the classification of stage I group should be revised in the new edition of lung cancer staging. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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